Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918650 | 0.93 | HDAC6 (0.46) | HPGDSHDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918802 | 0.91 | HDAC6 (0.55) | HPGDSHDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918557 | 0.91 | HDAC6 (0.49) | HPGDSHDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14917842 | 0.90 | HDAC6 (0.55) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL14918328 | 0.88 | HDAC6 (0.60) | HPGDSHDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918629 | 0.88 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL14917882 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL14918311 | 0.87 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL14918114 | 0.87 | HDAC6 (0.48) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL14918093 | 0.87 | HDAC6 (0.48) | HDAC6HDAC1HDAC8HDAC5HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066835-A2 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |