Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 15/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729285 | 0.84 | CHRM4 (0.57) | CHRM4CHRM5CHRM1CHRM2 | |
| SCHEMBL26126580 | 0.83 | CHRM4 (0.45) | CHRM4CHRM3CHRM5CHRM1CHRM2 | |
| SCHEMBL14932798 | 0.83 | CKS1B (0.54) | CHRM4CHRM3CHRM5CHRM1CHRM2 | |
| SCHEMBL1729015 | 0.81 | KDM4E (0.47) | CHRM4 | |
| SCHEMBL30549260 | 0.79 | PARP1 (0.45) | CHRM4CHRM3CHRM5CHRM1CHRM2 | |
| SCHEMBL1728729 | 0.79 | KDM4E (0.49) | — | |
| SCHEMBL26123479 | 0.79 | CHRM3 (0.46) | CHRM4CHRM3CHRM5CHRM1CHRM2 | |
| SCHEMBL16208933 | 0.77 | SCN9A (0.44) | — | |
| SCHEMBL17712642 | 0.75 | CHRM3 (0.45) | CHRM4CHRM3CHRM5CHRM1CHRM2 | |
| SCHEMBL14812128 | 0.74 | KDM4E (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066831-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |