Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 9/20 | 0.46 |
| ▸ | SKP1 | P63208 | 9/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 9/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728729 | 0.90 | KDM4E (0.49) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL1727998 | 0.87 | GPR119 (0.52) | GPR119CHRM4 | |
| SCHEMBL3266254 | 0.81 | GPR119 (0.41) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL14918149 | 0.81 | CHRM4 (0.47) | CHRM4 | |
| SCHEMBL3788594 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL1103982 | 0.79 | MAPK8 (0.47) | KDM4EGPR119 | |
| SCHEMBL11957018 | 0.78 | GPR119 (0.46) | KDM4EGPR119 | |
| SCHEMBL19438238 | 0.76 | GPR119 (0.47) | GPR119 | |
| SCHEMBL12036196 | 0.76 | KDM4E (0.46) | KDM4EHPGDHSD17B10GPR119 | |
| SCHEMBL17712603 | 0.76 | GPR119 (0.49) | KDM4EGPR119CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |