Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 11/20 | 0.53 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918767 | 0.98 | MAPT (0.51) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL25257007 | 0.81 | PLD1 (0.53) | ALDH1A1CYP1A2KDM4EHPGDHSD17B10 | |
| SCHEMBL353041 | 0.81 | ALDH1A1 (0.55) | MAPTALDH1A1LMNACNR2CYP1A2 | |
| SCHEMBL82447 | 0.76 | CNR2 (0.62) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL3573336 | 0.76 | GRIN2D (0.54) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL2744803 | 0.76 | UBE2T (0.54) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL1432610 | 0.76 | MAPT (0.53) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL1108644 | 0.76 | CNR2 (0.62) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL31196073 | 0.76 | GRIN2D (0.54) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL29656785 | 0.76 | CNR2 (0.76) | MAPTALDH1A1LMNAALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066835-A2 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |