Dimethylamine

Dimethylamine

SCHEMBL1491853

C=C(CCC)C(=O)O.CNC.CNC.I

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Dimethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.42
HDAC1 Q13547 4/20 0.42
HDAC2 Q92769 4/20 0.42
HDAC8 Q9BY41 4/20 0.42
FFAR3 O14843 3/20 0.42
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HDAC6 Q9UBN7 1/20 0.37
ALOX15 P16050 2/20 0.37
HSD17B10 Q99714 1/20 0.37
CTSD P07339 1/20 0.36
TET2 Q6N021 4/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
HAO1 Q9UJM8 1/20 0.33
THRB P10828 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL1033026 0.98 HDAC3 (0.43) HDAC3HDAC1HDAC2HDAC8FFAR3
Dimethylamine SCHEMBL7516845 0.95 HDAC3 (0.42) HDAC3HDAC1HDAC2HDAC8FFAR3
Dimethylamine SCHEMBL2982085 0.95 HDAC3 (0.42) HDAC3HDAC1HDAC2HDAC8FFAR3
Dimethylamine SCHEMBL12393363 0.93 HDAC3 (0.40) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL17818 0.90
SCHEMBL10862599 0.88 HDAC3 (0.40) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL20262532 0.87
Bromide SCHEMBL4851394 0.87
Ethylene SCHEMBL5835732 0.87 HDAC3 (0.48) HDAC3HDAC1HDAC2HDAC8FFAR3
Hydrochloric Acid SCHEMBL2564981 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3556989-A1 THROUGH TUBING BRIDGE PLUG AND INSTALLATION METHOD FOR SAME Halliburton Energy Services, Inc. (US) 2019-10-23 EP disclosed
EP-2483517-B1 ANCHOR ASSEMBLY AND METHOD FOR ANCHORING A DOWNHOLE TOOL HALLIBURTON ENERGY SERVICES INC (US) 2019-05-15 EP disclosed
EP-2483520-A1 THROUGH TUBING BRIDGE PLUG AND INSTALLATION METHOD FOR SAME Halliburton Energy Services, Inc. (US) 2012-08-08 EP disclosed
EP-2483517-A1 ANCHOR ASSEMBLY AND METHOD FOR ANCHORING A DOWNHOLE TOOL Halliburton Energy Services, Inc. (US) 2012-08-08 EP disclosed
EP-2483518-A1 COMPRESSION ASSEMBLY AND METHOD FOR ACTUATING DOWNHOLE PACKING ELEMENTS Halliburton Energy Services, Inc. (US) 2012-08-08 EP disclosed
EP-2483516-A1 ACTUATION ASSEMBLY AND METHOD FOR ACTUATING A DOWNHOLE TOOL Halliburton Energy Services, Inc. (US) 2012-08-08 EP disclosed
WO-2011037581-A1 THROUGH TUBING BRIDGE PLUG AND INSTALLATION METHOD FOR SAME HALLIBURTON ENERGY SERVICES, INC. (US) 2011-03-31 WO disclosed
WO-2011037582-A1 ACTUATION ASSEMBLY AND METHOD FOR ACTUATING A DOWNHOLE TOOL HALLIBURTON ENERGY SERVICES, INC. (US) 2011-03-31 WO disclosed
WO-2011037586-A1 COMPRESSION ASSEMBLY AND METHOD FOR ACTUATING DOWNHOLE PACKING ELEMENTS HALLIBURTON ENERGY SERVICES, INC. (US) 2011-03-31 WO disclosed
WO-2011037584-A1 ANCHOR ASSEMBLY AND METHOD FOR ANCHORING A DOWNHOLE TOOL HALLIBURTON ENERGY SERVICES, INC. (US) 2011-03-31 WO disclosed