Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14932809 | 0.88 | HDAC4 (0.56) | HDAC4HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL14918165 | 0.87 | HDAC4 (0.57) | HDAC4HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL14918519 | 0.85 | HDAC6 (0.58) | HDAC4HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL14917981 | 0.83 | HDAC6 (0.57) | HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL14932813 | 0.83 | HDAC4 (0.63) | HDAC4HDAC6HDAC8HDAC1HDAC5 | |
| Trifluoroacetic Acid SCHEMBL14918262 | 0.82 | HDAC6 (0.53) | HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL14918283 | 0.80 | HDAC4 (0.58) | HDAC4HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL14932814 | 0.80 | HDAC4 (0.65) | HDAC4HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL14918816 | 0.80 | HDAC6 (0.58) | HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL14932797 | 0.79 | HDAC6 (0.62) | HDAC4HDAC6HDAC8HDAC1HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066831-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |