SCHEMBL14918758 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	HDAC4	P56524	19/20	0.58

▸	HDAC6	Q9UBN7	18/20	0.58

▸	HDAC1	Q13547	16/20	0.58

▸	HDAC8	Q9BY41	14/20	0.58

▸	HDAC3	O15379	13/20	0.58

▸	HDAC7	Q8WUI4	13/20	0.58

▸	HDAC2	Q92769	13/20	0.58

▸	HDAC10	Q969S8	13/20	0.58

▸	HDAC11	Q96DB2	13/20	0.58

▸	HDAC9	Q9UKV0	13/20	0.58

▸	HDAC5	Q9UQL6	13/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14918755	1.00	HDAC4 (0.58)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14918798	0.93	HDAC6 (0.60)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14918801	0.93	HDAC6 (0.60)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14918579	0.88	HDAC6 (0.62)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14918576	0.88	HDAC6 (0.62)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14918266	0.87	HDAC6 (0.62)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14918264	0.87	HDAC6 (0.62)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14918014	0.83	HDAC4 (0.64)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14918017	0.83	HDAC4 (0.64)	HDAC4HDAC6HDAC1HDAC8HDAC3
SCHEMBL14917793	0.82	HDAC6 (0.62)	HDAC4HDAC6HDAC1HDAC8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013066831-A1	COMPOUNDS AND METHODS	GLAXOSMITHKLINE LLC (US)	2013-05-10	—	—	WO	disclosed