Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 18/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918017 | 1.00 | HDAC4 (0.64) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918274 | 0.85 | HDAC6 (0.65) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918275 | 0.85 | HDAC6 (0.65) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918758 | 0.83 | HDAC4 (0.58) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918755 | 0.83 | HDAC4 (0.58) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918266 | 0.79 | HDAC6 (0.62) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918264 | 0.79 | HDAC6 (0.62) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918579 | 0.78 | HDAC6 (0.62) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL14918576 | 0.78 | HDAC6 (0.62) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL12295761 | 0.78 | HDAC3 (1.00) | HDAC4HDAC6HDAC1HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066831-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |