SCHEMBL14919581

SCHEMBL14919581

C=CCCCCC(O)CCCCCCCCCC

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.67
ALDH1A1 P00352 2/20 0.52
USP2 O75604 2/20 0.50
FFAR4 Q5NUL3 2/20 0.50
FFAR1 O14842 2/20 0.50
CYP3A4 P08684 2/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GPR84 Q9NQS5 5/20 0.47
FAAH O00519 2/20 0.45
NFKB1 P19838 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11741042 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL11698081 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL9542809 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL13219935 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL19721792 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL9541562 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL15635268 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL3032108 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL20500832 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1
SCHEMBL9015418 1.00 TSHR (0.67) TSHRALDH1A1USP2FFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2773680-A1 PLASTICIZERS FOR ADHESIVE, COATING AND SEALANT COMPOSITIONS APPLIED TO ASPHALT Henry Company LLC (US) 2014-09-10 EP claimed
WO-2013067062-A1 PLASTICIZERS FOR ADHESIVE, COATING AND SEALANT COMPOSITIONS APPLIED TO ASPHALT HENRY COMPANY LLC (US) 2013-05-10 WO claimed
US-20250332112-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2025-10-30 US disclosed
EP-4574172-A2 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2025-06-25 EP disclosed
EP-4466250-B1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2025-03-26 EP disclosed
EP-4466250-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2024-11-27 EP disclosed
CN-118922401-A Ionizable cationic lipids for lipid nanoparticles 盖纳万科学有限公司 2024-11-08 CN disclosed
WO-2023144798-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2023-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332112-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES CETP, NPC1L1, ABCB4 TSHR 2640/4885ALDH1A1 3387/4885USP2 3954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.