Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389490 | 0.83 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10834880 | 0.82 | TSHR (0.52) | TSHRSMN1; SMN2 | |
| SCHEMBL1783884 | 0.80 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL5134464 | 0.80 | — | — | |
| SCHEMBL9770253 | 0.78 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL28054197 | 0.77 | — | — | |
| SCHEMBL231950 | 0.77 | — | — | |
| SCHEMBL7753360 | 0.77 | TSHR (0.43) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL28176167 | 0.76 | TSHR (0.43) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13042431 | 0.74 | TSHR (0.41) | TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012177469-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | claimed |
| WO-2012177591-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012177484-A1 | CATALYSTS FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012177485-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012177602-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012177469-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012177417-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| US-7906688-B2 | Calixarene bisphosphite ligand for use in hydroformylation processes | DOW GLOBAL TECHNOLOGIES INC. | 2011-03-15 | — | — | US | disclosed |
| US-20100044628-A1 | CALIXARENE BISPHOSPHITE LIGAND FOR USE IN HYDROFORMYLATION PROCESSES | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-25 | — | — | US | disclosed |
| WO-2008124468-A1 | A CALIXARENE BISPHOSPHITE LIGAND FOR USE IN HYDROFORMYLATION PROCESSES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044628-A1 | CALIXARENE BISPHOSPHITE LIGAND FOR USE IN HYDROFORMYLATION PROCESSES | CALU, PFKFB3, PFKFB4 | TSHR 3322/4885SMN1; SMN2 3591/4885ALDH1A1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.