Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817455 | 0.79 | — | — | |
| SCHEMBL25470339 | 0.79 | — | — | |
| SCHEMBL6446749 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL18606122 | 0.73 | — | — | |
| SCHEMBL14280108 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL2137763 | 0.73 | TET2 (0.39) | — | |
| SCHEMBL23950 | 0.73 | — | — | |
| SCHEMBL18896570 | 0.73 | — | — | |
| SCHEMBL21561098 | 0.71 | — | — | |
| SCHEMBL21970063 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241446-B2 | Thermoplastic single ply protective covering | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2012-08-14 | — | — | US | claimed |
| US-20110139340-A1 | Thermoplastic Single Ply Protective Covering | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2011-06-16 | — | — | US | claimed |
| US-7914868-B2 | Waterproof roof covering; extruded pressure sensitive adhesive rubber adhesive backing; mixture of butyl rubber and polyisobutylene, polybutylene | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2011-03-29 | — | — | US | claimed |
| US-20050183365-A1 | Thermoplastic single ply protective covering | BUILDING MATERIALS INVESTMENT CORPORATION | 2005-08-25 | — | — | US | claimed |
| US-20200140438-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AS ALLOSTERIC MODULATORS OF GROUP II METABOTROPIC GLUTAMATE RECEPTORS | DOMAIN THERAPEUTICS (FR) | 2020-05-07 | — | — | US | disclosed |
| US-8241446-B2 | Thermoplastic single ply protective covering | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2012-08-14 | — | — | US | disclosed |
| US-8044220-B2 | High shear process for the production of butadiene sulfone | H R D CORPORATION (US) | 2011-10-25 | — | — | US | disclosed |
| US-20110139340-A1 | Thermoplastic Single Ply Protective Covering | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2011-06-16 | — | — | US | disclosed |
| US-7914868-B2 | Waterproof roof covering; extruded pressure sensitive adhesive rubber adhesive backing; mixture of butyl rubber and polyisobutylene, polybutylene | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2011-03-29 | — | — | US | disclosed |
| US-20050183365-A1 | Thermoplastic single ply protective covering | BUILDING MATERIALS INVESTMENT CORPORATION | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140438-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AS ALLOSTERIC MODULATORS OF GROUP II METABOTROPIC GLUTAMATE RECEPTORS | GRM3, GRM1, GRM2 | THRB 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.