⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4589060 | 0.86 | — | — | |
| SCHEMBL4589062 | 0.86 | — | — | |
| SCHEMBL16108720 | 0.85 | SLC6A2 (0.54) | — | |
| SCHEMBL14934559 | 0.85 | SLC6A2 (0.54) | — | |
| SCHEMBL16108719 | 0.85 | SLC6A2 (0.54) | — | |
| SCHEMBL18771277 | 0.85 | SLC6A2 (0.54) | — | |
| SCHEMBL14920711 | 0.84 | PRCP (0.52) | — | |
| SCHEMBL14920569 | 0.84 | — | — | |
| SCHEMBL16143196 | 0.83 | SLC18A2 (0.54) | — | |
| SCHEMBL7084200 | 0.82 | SIGMAR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773637-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |