Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859664 | 0.84 | GRM4 (0.51) | GRM4MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL567361 | 0.82 | KMT2A (0.52) | GRM4KMT2AALDH1A1HTTLMNA | |
| SCHEMBL4993025 | 0.80 | GRM4 (0.51) | GRM4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29493429 | 0.76 | GAA (0.53) | GRM4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1278809 | 0.76 | MEN1 (0.54) | GRM4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2574273 | 0.76 | GRM4 (0.48) | GRM4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27463601 | 0.76 | GRM4 (0.51) | GRM4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL422433 | 0.76 | GRM4 (0.48) | GRM4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL568374 | 0.76 | GRM4 (0.48) | GRM4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28832845 | 0.75 | SMN1; SMN2 (0.46) | GRM4MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773613-A1 | SUBSTITUTED BENZYLAMINE COMPOUNDS, THEIR USE IN MEDICINE, AND IN PARTICULAR THE TREATMENT OF HEPATITIS C VIRUS (HCV) INFECTION | Astex Therapeutics Limited (GB) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064538-A1 | SUBSTITUTED BENZYLAMINE COMPOUNDS, THEIR USE IN MEDICINE, AND IN PARTICULAR THE TREATMENT OF HEPATITIS C VIRUS (HCV) INFECTION | ASTEX THERAPEUTICS LIMITED (GB) | 2013-05-10 | — | — | WO | disclosed |