Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993025 | 0.79 | GRM4 (0.51) | SMN1; SMN2GRM4NPSR1MEN1KMT2A | |
| SCHEMBL3666257 | 0.79 | GRM4 (0.42) | SMN1; SMN2GRM4NPSR1ACHEMEN1 | |
| SCHEMBL2574273 | 0.75 | GRM4 (0.48) | SMN1; SMN2GRM4MEN1KMT2AL3MBTL1 | |
| SCHEMBL29493429 | 0.75 | GAA (0.53) | SMN1; SMN2GRM4MEN1KMT2APKM | |
| SCHEMBL422433 | 0.75 | GRM4 (0.48) | SMN1; SMN2GRM4MEN1KMT2APKM | |
| SCHEMBL1278809 | 0.75 | MEN1 (0.54) | SMN1; SMN2GRM4MEN1KMT2APKM | |
| SCHEMBL27463601 | 0.75 | GRM4 (0.51) | SMN1; SMN2GRM4MEN1KMT2APKM | |
| SCHEMBL14920592 | 0.75 | GRM4 (0.51) | SMN1; SMN2GRM4MEN1KMT2AL3MBTL1 | |
| SCHEMBL28229556 | 0.73 | ACHE (0.44) | SMN1; SMN2NPSR1ACHEMEN1KMT2A | |
| SCHEMBL3439397 | 0.73 | GRM4 (0.46) | SMN1; SMN2GRM4MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958473-B | Amide compound, composition and application thereof | ADVINUS THERAPEUTICS LTD. (IN) | 2016-11-30 | — | — | CN | disclosed |