⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149206 | 1.00 | — | — | |
| SCHEMBL8593407 | 0.80 | — | — | |
| SCHEMBL8707961 | 0.80 | — | — | |
| SCHEMBL8593409 | 0.80 | — | — | |
| SCHEMBL8700267 | 0.78 | — | — | |
| SCHEMBL8700268 | 0.78 | — | — | |
| SCHEMBL9381006 | 0.78 | — | — | |
| SCHEMBL9381005 | 0.78 | — | — | |
| SCHEMBL2889952 | 0.76 | CES2 (0.48) | — | |
| SCHEMBL2889953 | 0.76 | CES2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838296-B1 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP (CA) | 2012-08-08 | — | — | EP | claimed |
| US-20240229089-A1 | A process for enzymatic synthesis of amides from amines and carboxylic acids or esters | XP CHEMISTRIES AB (SE) | 2024-07-11 | — | — | US | disclosed |
| US-20240208909-A1 | SUBSTITUTED QUINOLINE DERIVATIVES HAVING SOS1 INHIBITION ACTIVITIES AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-06-27 | — | — | US | disclosed |
| EP-3835298-B1 | NOVEL CHROMAN DERIVATIVES HAVING ESTROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC (US) | 2024-06-26 | — | — | EP | disclosed |
| US-12011445-B2 | Prevention of pancreatic cell degeneration | MELIOR PHARMACEUTICALS I, INC. (US) | 2024-06-18 | — | — | US | disclosed |
| WO-2024119028-A1 | SUBSTITUTED QUINOLINE DERIVATIVES HAVING SOS1 INHIBITION ACTIVITIES AND USES THEREOF | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| US-11999741-B2 | Process for the synthesis of 6-((3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-3-(tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one | CARDURION PHARMACEUTICALS, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-11992470-B2 | Stable aqueous capsaicin injectable formulations and medical uses thereof | CENTREXION THERAPEUTICS CORPORATION (US) | 2024-05-28 | — | — | US | disclosed |
| EP-4366833-A1 | CANCER THERAPEUTICS | Universitat de Barcelona (ES) | 2024-05-15 | — | — | EP | disclosed |
| US-20240140983-A1 | SINGLE STRANDED DNA ENZYME INHIBITORS | MASSEY UNIVERSITY (NZ) | 2024-05-02 | — | — | US | disclosed |
| WO-2002030884-A2 | SULFIDE AND DISULFIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002030860-A2 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002030863-A2 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002030882-A2 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| US-20020045639-A1 | COMBINATION OF HUPERZINE AND NICOTINIC COMPOUNDS AS A NEUROPROTECTIVE AGENT | US ARMY, SECRETARY OF THE ARMY | 2002-04-18 | — | — | US | disclosed |
| WO-2002011712-A2 | COMBINATION OF HUPERZINE AND NICOTINIC COMPOUNDS AS A NEUROPROTECTIVE AGENT | GEORGETOWN UNIVERSITY (US) | 2002-02-14 | — | — | WO | disclosed |
| WO-2000059855-A1 | ETHER COMPOUNDS, COMPOSITIONS, AND USES THEREOF | ESPERION THERAPEUTICS, INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-0003081-A2 | Thiazolidinecarbothioamides, their preparation, compositions and use as insecticides | ELI LILLY AND COMPANY (US) | 1979-07-25 | — | — | EP | disclosed |
| EP-0002938-A2 | Novel heterocyclic carbothioamides, compositions containing them, their preparation and use | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |
| EP-0002939-A2 | Novel carbothioamides, compositions containing them and their preparation | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |