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SCHEMBL14920840

SCHEMBL14920840

CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OCCOc1ccc(OC)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FKBP1A P62942 19/20 1.00
▸ FKBP5 Q13451 3/20 0.65
▸ FKBP4 Q02790 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14920841 1.00 FKBP1A (1.00) FKBP1AFKBP5FKBP4
SCHEMBL14933815 0.93 FKBP1A (0.87) FKBP1AFKBP5FKBP4
SCHEMBL5966173 0.85 FKBP1A (1.00) FKBP1AFKBP5FKBP4
SCHEMBL15436070 0.84 FKBP1A (0.73) FKBP1AFKBP5FKBP4
SCHEMBL19337370 0.82 FKBP1A (0.70) FKBP1AFKBP5FKBP4
SCHEMBL6684784 0.82 FKBP1A (1.00) FKBP1AFKBP5FKBP4
SCHEMBL14920732 0.82 FKBP1A (0.72) FKBP1AFKBP5FKBP4
SCHEMBL7400429 0.81 FKBP1A (1.00) FKBP1A
SCHEMBL5833651 0.80 FKBP1A (1.00) FKBP1AFKBP5FKBP4
SCHEMBL19337325 0.80 FKBP1A (0.66) FKBP1AFKBP5FKBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013064703-A9 FKBP SUBTYPE-SPECIFIC RAPAMYCIN ANALOGUE FOR USE IN TREATMENT OF DISEASES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-06-27 — — WO disclosed
WO-2013064703-A2 FKBP SUBTYPE-SPECIFIC RAPAMYCIN ANALOGUE FOR USE IN TREATMENT OF DISEASES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-05-10 — — WO disclosed