Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188191 | 0.84 | SLC6A4 (0.41) | SLC6A3SLC6A4FPR2FFAR1 | |
| SCHEMBL2188196 | 0.84 | SLC6A4 (0.41) | SLC6A3SLC6A4FPR2FFAR1 | |
| SCHEMBL2188200 | 0.84 | SLC6A4 (0.41) | SLC6A3SLC6A4FPR2FFAR1 | |
| SCHEMBL3184339 | 0.83 | SLC6A2 (0.48) | KDM1ASLC6A4FFAR1EPHX1 | |
| SCHEMBL3184345 | 0.83 | SLC6A2 (0.48) | KDM1ASLC6A4FFAR1EPHX1 | |
| SCHEMBL3184354 | 0.83 | SLC6A2 (0.48) | KDM1ASLC6A4FFAR1EPHX1 | |
| SCHEMBL16141290 | 0.82 | SLC6A3 (0.50) | SLC6A3SLC6A4 | |
| SCHEMBL16141289 | 0.82 | SLC6A3 (0.50) | SLC6A3SLC6A4 | |
| SCHEMBL14934470 | 0.82 | SLC6A3 (0.50) | SLC6A3SLC6A4 | |
| SCHEMBL16108268 | 0.82 | SLC6A3 (0.50) | SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773637-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |