Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.59 |
| ▸ | FABP3 | P05413 | 5/20 | 0.59 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MAP2 | P11137 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920869 | 0.94 | FABP4 (0.51) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL14916908 | 0.88 | FABP4 (0.50) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL14916792 | 0.82 | FABP4 (0.59) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL14916391 | 0.82 | FABP4 (0.43) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL14916844 | 0.81 | FABP4 (0.62) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL9363382 | 0.78 | FABP4 (0.69) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL14917310 | 0.78 | FABP4 (0.69) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL14916340 | 0.78 | FABP4 (0.54) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL14917376 | 0.76 | FABP4 (0.72) | FABP4FABP3FABP5PLA2G2ADHODH | |
| SCHEMBL14916797 | 0.76 | FABP4 (0.73) | FABP4FABP3FABP5PLA2G2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773619-A1 | NEW ARYL-QUINOLINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064465-A1 | NEW ARYL-QUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-10 | — | — | WO | disclosed |