Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219248 | 0.87 | ACHE (0.36) | ACHENTSR1 | |
| SCHEMBL13219244 | 0.86 | HRH3 (0.37) | ACHENTSR1S1PR1 | |
| SCHEMBL3039685 | 0.85 | ACHE (0.40) | ACHES1PR1 | |
| SCHEMBL3207524 | 0.84 | ACHE (0.41) | ACHES1PR1 | |
| SCHEMBL3037071 | 0.84 | ACHE (0.37) | ACHENTSR1S1PR1 | |
| SCHEMBL3036600 | 0.84 | ACHE (0.36) | ACHES1PR1 | |
| SCHEMBL12022729 | 0.84 | ACHE (0.40) | ACHES1PR1 | |
| Methylene Chloride SCHEMBL3209457 | 0.83 | ACHE (0.39) | ACHES1PR1 | |
| Methylene Chloride SCHEMBL3037402 | 0.82 | ACHE (0.38) | ACHES1PR1 | |
| SCHEMBL3037414 | 0.81 | TP53 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436184-B2 | 6-(biphenyl-ester)-3H-naphtho[2,1-b]pyrans as photochromic dichroic dyes and optical article containing them | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE (FR) | 2013-05-07 | — | — | US | disclosed |