Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846290 | 0.87 | ADORA2A (0.60) | ADORA2A | |
| SCHEMBL8275730 | 0.86 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL29361733 | 0.86 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL14922336 | 0.83 | ADORA2A (0.74) | ADORA2A | |
| SCHEMBL2853601 | 0.82 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL23868397 | 0.81 | ADORA2A (0.69) | ADORA2A | |
| SCHEMBL2847453 | 0.81 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL13345171 | 0.80 | ADORA2A (0.79) | ADORA2A | |
| SCHEMBL18211390 | 0.80 | ADORA2A (0.85) | ADORA2A | |
| SCHEMBL13345180 | 0.79 | ADORA2A (0.78) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44205-E1 | Adenosine A2a receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-05-07 | — | — | US | disclosed |
| US-RE44205-E1 | Adenosine A2a receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-05-07 | — | — | US | disclosed |