Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922332 | 0.83 | ADORA2A (0.75) | ADORA2A | |
| SCHEMBL23691676 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1 | |
| SCHEMBL13344969 | 0.78 | ADORA2A (0.81) | ADORA2AADORA1 | |
| SCHEMBL12404398 | 0.77 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL12969859 | 0.77 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL8243358 | 0.76 | ADORA2A (0.85) | ADORA2AADORA1 | |
| SCHEMBL14922329 | 0.76 | ADORA2A (0.91) | ADORA2AADORA1 | |
| SCHEMBL21833380 | 0.75 | ADORA2A (0.79) | ADORA2AADORA1 | |
| SCHEMBL21833198 | 0.75 | ADORA2A (0.79) | ADORA2AADORA1 | |
| SCHEMBL7333945 | 0.75 | ADORA2A (0.71) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44205-E1 | Adenosine A2a receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-05-07 | — | — | US | disclosed |
| US-RE44205-E1 | Adenosine A2a receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-05-07 | — | — | US | disclosed |