Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922631 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDGLAPTGDR2HTT | |
| SCHEMBL12197476 | 0.94 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDGLAPTGDR2HTT | |
| SCHEMBL14922680 | 0.94 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDGLAHTTTDP1 | |
| SCHEMBL12197461 | 0.94 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDGLAPTGDR2HTT | |
| SCHEMBL14922689 | 0.94 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDGLAHTTTDP1 | |
| SCHEMBL12223619 | 0.94 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDGLAPTGDR2HTT | |
| SCHEMBL14922603 | 0.94 | SCN9A (0.38) | SMN1; SMN2HPGDGLATDP1MAPK1 | |
| SCHEMBL14922683 | 0.94 | SCN9A (0.38) | SMN1; SMN2HPGDGLATDP1MAPK1 | |
| SCHEMBL22277456 | 0.93 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDGLAPTGDR2HTT | |
| SCHEMBL14922583 | 0.92 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDGLAPTGDR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |