Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922689 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14922603 | 0.95 | SCN9A (0.38) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14922683 | 0.95 | SCN9A (0.38) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14922394 | 0.94 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14922631 | 0.94 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14922591 | 0.93 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14922685 | 0.93 | SCN9A (0.39) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14922635 | 0.93 | SCN9A (0.39) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL22277517 | 0.90 | GABRA1 (0.32) | ALDH1A1LMNAFFAR4HTR2CHTR2B | |
| SCHEMBL22277456 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |