SCHEMBL14922641

SCHEMBL14922641

CCCOc1ccc(C2=CCC(c3ccc(C4=CCC(c5ccc(OCC)c(F)c5F)CC4)c(F)c3F)CC2)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 5/20 0.34
HTR2B P41595 5/20 0.34
HTR2A P28223 1/20 0.34
FPR2 P25090 7/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15381683 0.99 FPR2 (0.35) HTR2CHTR2BHTR2AFPR2MEN1
SCHEMBL15381651 0.99 FPR2 (0.35) HTR2CHTR2BHTR2AFPR2MEN1
SCHEMBL14922597 0.98 HTR2C (0.33) HTR2CHTR2BHTR2AFPR2
SCHEMBL14922502 0.98 HTR2C (0.33) HTR2CHTR2BHTR2AFPR2
SCHEMBL14922514 0.94 MEN1 (0.32) FPR2MEN1KMT2A
SCHEMBL1242654 0.94 MEN1 (0.32) FPR2MEN1KMT2A
SCHEMBL14922513 0.94 FPR2 (0.32) HTR2AFPR2
SCHEMBL15381812 0.94 HTR2C (0.31) HTR2CHTR2BHTR2AFPR2
SCHEMBL15381514 0.93 FPR2 (0.33) FPR2MEN1KMT2A
SCHEMBL15381685 0.93 FPR2 (0.33) FPR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8435422-B2 Five-ring compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-05-07 US disclosed