Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15381743 | 0.97 | SCN9A (0.39) | SCN9ACNR2CNR1TSHRMEN1 | |
| SCHEMBL15381616 | 0.97 | SCN9A (0.39) | SCN9ACNR2CNR1TSHRMEN1 | |
| SCHEMBL14922672 | 0.95 | FPR2 (0.33) | SCN9ACNR2CNR1MEN1KMT2A | |
| SCHEMBL15381537 | 0.95 | SCN9A (0.40) | SCN9ACNR2CNR1TSHRLMNA | |
| SCHEMBL15381730 | 0.95 | SCN9A (0.40) | SCN9ACNR2CNR1TSHRLMNA | |
| SCHEMBL14922594 | 0.94 | MAPT (0.36) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL12197268 | 0.94 | SCN9A (0.35) | SCN9ACNR2CNR1TSHRLMNA | |
| SCHEMBL14922593 | 0.93 | SCN9A (0.41) | SCN9ACNR2CNR1TSHRMEN1 | |
| SCHEMBL15381784 | 0.92 | CNR1 (0.35) | SCN9ACNR2CNR1MEN1KMT2A | |
| SCHEMBL15381526 | 0.92 | CNR1 (0.35) | SCN9ACNR2CNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |