Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 10/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243236 | 1.00 | HTR2A (0.40) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL1242479 | 1.00 | HTR2A (0.40) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12740618 | 0.96 | CNR2 (0.38) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12735766 | 0.96 | CNR2 (0.38) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL10303139 | 0.94 | FPR2 (0.39) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL15381684 | 0.94 | ALOX5AP (0.40) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12735782 | 0.94 | SCN9A (0.44) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12740624 | 0.94 | SCN9A (0.44) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL15381722 | 0.94 | ALOX5AP (0.40) | HTR2AHTR2CHTR2BCNR2SCN9A | |
| SCHEMBL12197071 | 0.93 | HTR2A (0.36) | HTR2AHTR2CHTR2BCNR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |