Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922635 | 1.00 | SCN9A (0.39) | SCN9ATSHRLMNAALDH1A1RAB9A | |
| SCHEMBL14922683 | 0.98 | SCN9A (0.38) | SCN9ATSHRLMNAALDH1A1RAB9A | |
| SCHEMBL14922603 | 0.98 | SCN9A (0.38) | SCN9ATSHRLMNAALDH1A1RAB9A | |
| SCHEMBL2509034 | 0.97 | SCN9A (0.37) | SCN9ALMNAALDH1A1MEN1KMT2A | |
| SCHEMBL12197468 | 0.95 | SCN9A (0.36) | SCN9ATSHRLMNAALDH1A1RAB9A | |
| SCHEMBL12196509 | 0.95 | SCN9A (0.36) | SCN9ATSHRLMNAALDH1A1RAB9A | |
| SCHEMBL14922680 | 0.93 | SMN1; SMN2 (0.36) | SCN9ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14922689 | 0.93 | SMN1; SMN2 (0.36) | SCN9ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14922674 | 0.93 | SCN9A (0.38) | SCN9ATSHRLMNAALDH1A1RAB9A | |
| SCHEMBL14922608 | 0.93 | SCN9A (0.38) | SCN9ATSHRLMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |