SCHEMBL14922774

SCHEMBL14922774

Cc1ccc(-c2cccc3c2-c2c(cccc2-c2ccc(C)cc2)C3=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.47
MAPK1 P28482 6/20 0.46
TSHR P16473 4/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
HPGDS O60760 1/20 0.46
TP53 P04637 1/20 0.46
PKM P14618 1/20 0.46
AGTR1 P30556 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
POLB P06746 1/20 0.46
EDNRB P24530 1/20 0.45
EDNRA P25101 1/20 0.45
MAPT P10636 5/20 0.44
TDP1 Q9NUW8 5/20 0.44
ALDH1A1 P00352 4/20 0.44
CYP3A4 P08684 2/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12114171 0.91 ELANE (0.54) ELANEMAPK1TSHRRAB9ANPC1
SCHEMBL5012339 0.90 ELANE (0.52) ELANEMAPK1TSHRRAB9ANPC1
SCHEMBL16656184 0.84 CA1 (0.44) ELANEMAPK1TSHRRAB9ANPC1
SCHEMBL10583614 0.84 ELANE (0.46) ELANEMAPK1TSHRRAB9ANPC1
SCHEMBL9018851 0.81 ELANE (0.55) ELANEMAPK1TSHRRAB9ANPC1
SCHEMBL22187708 0.79 MEN1 (0.52) MAPK1TSHRRAB9ANPC1MEN1
SCHEMBL12114247 0.79 MAPT (0.54) ELANEMAPK1TSHRRAB9ANPC1
SCHEMBL12114167 0.79 ELANE (0.50) ELANEMAPK1TSHRRAB9ANPC1
SCHEMBL12111190 0.78 ELANE (0.47) ELANEMAPK1TSHRRAB9ANPC1
SCHEMBL20618707 0.77 POLB (0.60) ELANEMAPK1TSHRRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465889-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-06-18 US disclosed
US-8435706-B2 2013-05-07 US disclosed