SCHEMBL22187708

SCHEMBL22187708

O=C1c2cccc(-c3ccccc3)c2-c2c1cccc2-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CDC25B P30305 2/20 0.52
HDAC4 P56524 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
ALDH1A1 P00352 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
ADORA2A P29274 2/20 0.50
MAPT P10636 6/20 0.48
MAPK1 P28482 5/20 0.48
NSD2 O96028 2/20 0.48
KDM4E B2RXH2 2/20 0.48
LMNA P02545 4/20 0.48
TDP1 Q9NUW8 3/20 0.48
HTT P42858 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MAOA P21397 3/20 0.48
HPGD P15428 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12626745 0.93 MAPT (0.52) MEN1KMT2ACDC25BHDAC4HDAC2
SCHEMBL16491897 0.91 MEN1 (0.55) MEN1KMT2ACDC25BHDAC4HDAC2
SCHEMBL1038974 0.91 ADORA2A (0.57) MEN1KMT2ACDC25BHDAC4HDAC2
SCHEMBL11424452 0.90 HDAC4 (0.52) MEN1KMT2ACDC25BHDAC4HDAC2
Ammonia Solution, Strong SCHEMBL27523091 0.89 ADORA2A (0.55) MEN1KMT2ACDC25BHDAC4HDAC2
SCHEMBL27971257 0.88 HDAC4 (0.50) MEN1KMT2ACDC25BHDAC4HDAC2
SCHEMBL19001856 0.87 L3MBTL1 (0.52) MEN1KMT2ACDC25BHDAC4HDAC2
SCHEMBL8091836 0.87 HDAC4 (0.45) MEN1KMT2ACDC25BHDAC4HDAC2
SCHEMBL24736915 0.85 HDAC4 (0.52) MEN1KMT2ACDC25BHDAC4HDAC2
SCHEMBL29976182 0.85 HDAC4 (0.52) MEN1KMT2ACDC25BHDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3677614-B1 THERMOPLASTIC RESIN AND OPTICAL MEMBER TEIJIN LTD (JP) 2026-05-27 EP disclosed
CN-110741030-B Thermoplastic resin and optical member 帝人株式会社 2022-06-17 CN disclosed
US-11261294-B2 Thermoplastic resin and optical member TEIJIN LIMITED (JP) 2022-03-01 US disclosed
US-20210147621-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER TEIJIN LIMITED (JP) 2021-05-20 US disclosed
WO-2020248943-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2020-12-17 WO disclosed
EP-3677614-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER Teijin Limited (JP) 2020-07-08 EP disclosed
CN-110741030-A Thermoplastic resin and optical member 帝人株式会社 2020-01-31 CN disclosed