Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477224 | 0.88 | FFAR1 (0.54) | CYP2D6CYP2C9CYP2C19RECQLCYP1A2 | |
| SCHEMBL2335514 | 0.87 | TSHR (0.49) | CYP2D6CYP2C9CYP2C19RECQLTSHR | |
| SCHEMBL1861986 | 0.84 | MMP1 (0.52) | CYP2C19TSHRMAOBCYP1A2SMN1; SMN2 | |
| SCHEMBL2830701 | 0.83 | TSHR (0.57) | CYP2D6CYP2C9CYP2C19RECQLTSHR | |
| SCHEMBL2828262 | 0.82 | CYP2D6 (0.54) | CYP2D6CYP2C9CYP2C19RECQLTSHR | |
| SCHEMBL1204525 | 0.82 | CYP2D6 (0.54) | CYP2D6CYP2C9CYP2C19RECQLTSHR | |
| SCHEMBL10341513 | 0.82 | CYP2D6 (0.54) | CYP2D6CYP2C9CYP2C19RECQLTSHR | |
| SCHEMBL1204526 | 0.82 | CYP2D6 (0.54) | CYP2D6CYP2C9CYP2C19RECQLTSHR | |
| SCHEMBL29179989 | 0.81 | TSHR (0.51) | CYP2D6CYP2C9CYP2C19RECQLTSHR | |
| SCHEMBL30811232 | 0.81 | TSHR (0.51) | CYP2D6CYP2C9CYP2C19RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910270-B1 | COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD | NOGRA PHARMA LTD (IE) | 2013-05-08 | — | — | EP | disclosed |