SCHEMBL14923019

SCHEMBL14923019

CC(C)C(C)(c1ccc(BOC(C)(C)C(C)(C)O)cc1)c1ccc(O)cn1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14396912 0.76 ALOX5AP (0.43) ALOX5AP
SCHEMBL14397148 0.76 ALOX5AP (0.43) ALOX5AP
SCHEMBL705390 0.75 ALOX5AP (0.43) ALOX5AP
SCHEMBL8281890 0.74 ESR1 (0.37)
SCHEMBL25646278 0.71
SCHEMBL706427 0.70 ALOX5AP (0.37) ALOX5AP
SCHEMBL22084822 0.68
SCHEMBL10197150 0.68 ALOX5AP (0.70) ALOX5AP
SCHEMBL480305 0.68 ALOX5AP (0.69) ALOX5AP
SCHEMBL18428342 0.67 PTGS1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013174-B1 DIARYL SUBSTITUTED ALKANES MERCK SHARP & DOHME (US) 2013-05-08 EP disclosed