Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14396912 | 1.00 | ALOX5AP (0.43) | ALOX5APACHEDEGS1TSHRESR1 | |
| SCHEMBL705390 | 0.86 | ALOX5AP (0.43) | ALOX5APDEGS1TSHRESR1ESR2 | |
| SCHEMBL10199332 | 0.78 | ALOX5AP (0.47) | ALOX5APMEN1KMT2A | |
| SCHEMBL10198932 | 0.77 | ALOX5AP (0.51) | ALOX5AP | |
| SCHEMBL706427 | 0.77 | ALOX5AP (0.37) | ALOX5AP | |
| SCHEMBL14923019 | 0.76 | ALOX5AP (0.39) | ALOX5AP | |
| SCHEMBL707619 | 0.76 | ALOX5AP (0.56) | ALOX5APDEGS1HPGDALDH1A1 | |
| SCHEMBL13262159 | 0.75 | ALOX5AP (0.49) | ALOX5APLMNA | |
| SCHEMBL480305 | 0.75 | ALOX5AP (0.69) | ALOX5APCYP3A4ALDH1A1 | |
| SCHEMBL10197150 | 0.75 | ALOX5AP (0.70) | ALOX5APDEGS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120574-A2 | DIARYL SUBSTITUTED ALKANES | MERCK & CO., INC. (US) | 2007-10-25 | — | — | WO | disclosed |