Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031926 | 0.84 | PCSK9 (0.34) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL21148081 | 0.83 | ORAI1 (0.37) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL23542803 | 0.81 | — | — | |
| SCHEMBL21778882 | 0.78 | — | — | |
| SCHEMBL23570765 | 0.76 | CA4 (0.32) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL21147723 | 0.69 | TRPV6 (0.41) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL14234423 | 0.68 | AKT1 (0.38) | — | |
| SCHEMBL23219892 | 0.68 | PCSK9 (0.35) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL12290395 | 0.68 | — | — | |
| SCHEMBL23026435 | 0.67 | CA4 (0.30) | PCSK9ORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725079-B1 | COMPOSITION FOR CHARGE-TRANSPORTING FILM AND ION COMPOUND, CHARGE-TRANSPORTING FILM AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME, AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PRODUCING CHARGE-TRANSPORTING FILM | MITSUBISHI CHEM CORP (JP) | 2013-05-08 | — | — | EP | disclosed |