Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290209 | 0.81 | SMN1; SMN2 (0.35) | CNR1TYMPFAAHHEXAHEXB | |
| SCHEMBL10659784 | 0.69 | DNM1 (0.41) | — | |
| SCHEMBL13722712 | 0.68 | — | — | |
| SCHEMBL8219644 | 0.67 | CYP19A1 (0.38) | KDM4EPKM | |
| SCHEMBL7515622 | 0.64 | SMN1; SMN2 (0.34) | CNR1KDM4EPKM | |
| SCHEMBL12172691 | 0.64 | CNR1 (0.37) | CNR1FAAHPTGS1PTGS2MGLL | |
| SCHEMBL8222748 | 0.64 | CYP19A1 (0.38) | KDM4EPKM | |
| SCHEMBL7528765 | 0.63 | PTGS1 (0.42) | PTGS1PTGS2 | |
| SCHEMBL7513062 | 0.62 | SMN1; SMN2 (0.35) | CNR1TYMPFAAHKDM4EPKM | |
| SCHEMBL4620224 | 0.62 | CNR1 (0.38) | CNR1FAAHKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699455-B1 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2013-05-08 | — | — | EP | disclosed |