Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222375 | 0.76 | KDM4E (0.52) | MMP2MMP9NFKB1 | |
| SCHEMBL221188 | 0.76 | KDM4E (0.52) | MMP2MMP9NFKB1 | |
| SCHEMBL2601956 | 0.74 | KDM4E (0.46) | — | |
| SCHEMBL13644404 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL21294258 | 0.73 | CYP2A6 (0.46) | — | |
| SCHEMBL13644405 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL21294259 | 0.73 | CYP2A6 (0.46) | — | |
| SCHEMBL2564338 | 0.72 | ALDH1A1 (0.56) | — | |
| SCHEMBL2564332 | 0.72 | ALDH1A1 (0.56) | — | |
| SCHEMBL11261129 | 0.71 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035988-B2 | Enone reductases | CODEXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20170175087-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-06-22 | — | — | US | disclosed |
| US-9617568-B2 | Enone reductases | CODEXIS, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160273007-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2016-09-22 | — | — | US | disclosed |
| US-9388438-B2 | Enone reductases | CODEXIS, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150315613-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-11-05 | — | — | US | disclosed |
| US-9121045-B2 | Enone reductases | CODEXIS, INC. (US) | 2015-09-01 | — | — | US | disclosed |
| US-20150031095-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-01-29 | — | — | US | disclosed |
| US-8883475-B2 | Enone reductases | CODEXIS, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130115663-A1 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2013-05-09 | — | — | US | disclosed |