SCHEMBL14924835

SCHEMBL14924835

CCC(C)(C)C(=O)OCC(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 9/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14962511 0.84 RIPK1 (0.43) RIPK1HTTL3MBTL1
SCHEMBL14962526 0.83 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL106867 0.82 RIPK1 (0.37) RIPK1TSHRSMN1; SMN2
SCHEMBL14962524 0.81 RIPK1 (0.33) RIPK1
SCHEMBL14962527 0.80 RIPK1 (0.43) RIPK1KDM4ELMNAMAPK1HTT
SCHEMBL14867071 0.77 TSHR (0.33) RIPK1TSHRSMN1; SMN2CYP4F2CYP4A11
SCHEMBL14747379 0.75 RIPK1 (0.33) RIPK1KDM4ELMNAMAPK1HTT
SCHEMBL14649752 0.74 GAA (0.44) LMNATSHRCYP4F2CYP4A11
SCHEMBL2607778 0.74 TET2 (0.38) LMNAL3MBTL1TSHRCYP4F2CYP4A11
SCHEMBL14962530 0.74 RIPK1 (0.33) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034558-B2 Actinic-ray- or radiation-sensitive resin composition, actinic-ray- or radiation-sensitive film and method of forming pattern FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-20130115557-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2013-05-09 US disclosed