SCHEMBL14926657

SCHEMBL14926657

COCCOc1ccc(-c2ccc(-c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 6/20 0.50
DRD4 P21917 6/20 0.50
DRD3 P35462 6/20 0.50
L3MBTL1 Q9Y468 1/20 0.48
NPC1 O15118 2/20 0.46
HPGD P15428 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
ACHE P22303 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
KCNH2 Q12809 2/20 0.43
CHEK2 O96017 1/20 0.43
FFAR4 Q5NUL3 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926625 1.00 DRD2 (0.50) DRD2DRD4DRD3L3MBTL1NPC1
SCHEMBL21025623 0.94 KDM4E (0.50) DRD2DRD4DRD3L3MBTL1NPC1
SCHEMBL6445608 0.94 DRD2 (0.55) DRD2DRD4DRD3L3MBTL1NPC1
SCHEMBL13554406 0.91 CYP3A4 (0.50) CYP3A4CYP2D6CHEK2
SCHEMBL21185868 0.91 DRD2 (0.57) DRD2DRD4DRD3L3MBTL1NPC1
SCHEMBL29345524 0.90 DRD2 (0.53) DRD2DRD4DRD3L3MBTL1NPC1
SCHEMBL15581288 0.88 DRD2 (0.52) DRD2DRD4DRD3L3MBTL1NPC1
SCHEMBL12549929 0.88 DRD2 (0.52) DRD2DRD4DRD3L3MBTL1NPC1
SCHEMBL15581256 0.88 DRD2 (0.52) DRD2DRD4DRD3L3MBTL1NPC1
SCHEMBL21897674 0.88 KDM4E (0.54) DRD2DRD4DRD3L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20160274418-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2016-09-22 US disclosed
US-9360708-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2016-06-07 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed