SCHEMBL14926681

SCHEMBL14926681

COc1cc(C)ccc1N=Nc1ccc(C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.53
▸ NPC1 O15118 6/20 0.53
▸ RAB9A P51151 6/20 0.53
▸ L3MBTL1 Q9Y468 5/20 0.53
▸ MAPK1 P28482 5/20 0.53
▸ PKM P14618 1/20 0.53
▸ ATM Q13315 1/20 0.53
▸ ACHE P22303 1/20 0.50
▸ MEN1 O00255 9/20 0.47
▸ KMT2A Q03164 9/20 0.47
▸ HSP90AA1 P07900 2/20 0.47
▸ TDP1 Q9NUW8 5/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ APOBEC3A P31941 2/20 0.43
▸ APOBEC3G Q9HC16 2/20 0.43
▸ FTO Q9C0B1 1/20 0.42
▸ PHLPP2 Q6ZVD8 1/20 0.42
▸ CYP3A4 P08684 1/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ STAT3 P40763 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926690 1.00 MAPT (0.53) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL14930477 0.98 MAPT (0.54) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL14926695 0.91 MAPT (0.49) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL23559947 0.90 KMT2A (0.60) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL12307309 0.87 NPC1 (0.54) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL17780684 0.81 MAPT (0.45) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL16684222 0.80 MAPT (0.56) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL17133382 0.79 ACHE (0.52) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL17787274 0.79 MEN1 (0.50) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL21426906 0.79 NPC1 (0.46) MAPTNPC1RAB9AL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210191170-A1 OPTICAL DEVICE AND REFRESH DRIVING METHOD FOR OPTICAL DEVICE KYOTO UNIVERSITY (JP) 2021-06-24 — — US disclosed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 — — US disclosed
US-20200241336-A1 COMPLEX AND OPTICAL ELEMENT KYOTO UNIVERSITY (JP) 2020-07-30 — — US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 — — US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 — — US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 — — US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 — — US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 — — US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 — — US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 — — US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 — — US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 — — US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 — — US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 — — US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 — — US disclosed
Send feedback