SCHEMBL14926693

SCHEMBL14926693

Cc1ccc(N=Nc2ccc(N=Nc3ccc(C)c(C)c3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.48
RAB9A P51151 9/20 0.48
MAPT P10636 7/20 0.48
MAPK1 P28482 4/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
PKM P14618 1/20 0.48
ATM Q13315 1/20 0.48
TDP1 Q9NUW8 5/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
STAT3 P40763 1/20 0.47
STAT1 P42224 1/20 0.47
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
NSD2 O96028 1/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18590719 1.00 NPC1 (0.48) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL14926676 1.00 NPC1 (0.48) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL14926694 0.93 NPC1 (0.44) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL31264508 0.90 KMT2A (0.45) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL11516839 0.90 KMT2A (0.45) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL11516843 0.90 KMT2A (0.45) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL15682379 0.84 ALDH1A1 (0.55) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL31264554 0.84 ALDH1A1 (0.55) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL17446281 0.82 NPC1 (0.61) NPC1RAB9AMAPTMAPK1L3MBTL1
SCHEMBL1405393 0.82 NPC1 (0.61) NPC1RAB9AMAPTMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210191170-A1 OPTICAL DEVICE AND REFRESH DRIVING METHOD FOR OPTICAL DEVICE KYOTO UNIVERSITY (JP) 2021-06-24 US disclosed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 US disclosed
US-20200241336-A1 COMPLEX AND OPTICAL ELEMENT KYOTO UNIVERSITY (JP) 2020-07-30 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed