Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930663 | 0.89 | FYN (0.39) | FYNIKBKBKDM4EALDH1A1HPGD | |
| SCHEMBL14926993 | 0.71 | PTAFR (0.51) | — | |
| SCHEMBL14903983 | 0.68 | PDGFRB (0.54) | FYN | |
| SCHEMBL14927047 | 0.68 | FYN (0.38) | FYNIKBKBHTTKDM4EALDH1A1 | |
| SCHEMBL14903973 | 0.67 | PTAFR (0.40) | FYNHTTALDH1A1 | |
| SCHEMBL14903984 | 0.66 | FYN (0.38) | FYNIKBKBPDCD1CD274HTT | |
| SCHEMBL14904054 | 0.65 | PDGFRB (0.55) | FYN | |
| SCHEMBL14903972 | 0.64 | PTAFR (0.40) | FYNIKBKBKDM4EALDH1A1HPGD | |
| SCHEMBL14904012 | 0.64 | FYN (0.43) | FYNPDCD1CD274 | |
| SCHEMBL14904334 | 0.63 | FYN (0.34) | FYNIKBKBPDCD1CD274HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | FYN 3983/4885IKBKB 3606/4885PDCD1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.