Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCLC | P48506 | 1/20 | 0.82 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.72 |
| ▸ | GLUL | P15104 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15965757 | 0.84 | GCLC (0.57) | GCLCFOLH1GRIK1SLC1A3SLC1A2 | |
| SCHEMBL14155152 | 0.84 | FOLH1 (0.78) | GCLCFOLH1GLULGRM8GRM6 | |
| SCHEMBL10134655 | 0.84 | FOLH1 (1.00) | GCLCFOLH1GRM8GRM6GRM7 | |
| SCHEMBL15278193 | 0.84 | FOLH1 (1.00) | GCLCFOLH1GRM8GRM6GRM7 | |
| SCHEMBL4088761 | 0.82 | FOLH1 (0.74) | GCLCFOLH1GLULGRM8GRM6 | |
| SCHEMBL4095796 | 0.82 | FOLH1 (0.74) | GCLCFOLH1GLULGRM8GRM6 | |
| SCHEMBL11959173 | 0.81 | GCLC (0.54) | GCLCFOLH1GRIK1SLC1A3SLC1A2 | |
| SCHEMBL2742758 | 0.79 | CHRM1 (0.58) | GCLCFOLH1GRIK1SLC1A3SLC1A2 | |
| SCHEMBL22914515 | 0.79 | GCLC (0.69) | GCLCFOLH1GLULGRM8GRM6 | |
| SCHEMBL10597403 | 0.79 | GCLC (0.69) | GCLCFOLH1GLULGRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049709-A1 | THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME | PFIZER INC. | 2017-02-23 | — | — | US | disclosed |
| US-8734846-B2 | Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic targeted nanoparticles | BIND BIOSCIENCES, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130115192-A1 | Methods for the Preparation of Targeting Agent Functionalized Diblock Copolymers for Use in Fabrication of Therapeutic Targeted Nanoparticles | BIND BIOSCIENCES, INC (US) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130115192-A1 | Methods for the Preparation of Targeting Agent Functionalized Diblock Copolymers for Use in Fabrication of Therapeutic Targeted Nanoparticles | GNE, PAM, EPHA2 | GCLC 1651/4885FOLH1 727/4885GLUL 3041/4885 |
| US-20170049709-A1 | THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME | CTSA, GAA, EEA1 | GCLC 2788/4885FOLH1 135/4885GLUL 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.