⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428133 | 1.00 | — | — | |
| SCHEMBL11956274 | 0.83 | ALOX5 (0.42) | — | |
| SCHEMBL7874405 | 0.80 | — | — | |
| SCHEMBL9325784 | 0.78 | — | — | |
| SCHEMBL14928381 | 0.78 | — | — | |
| SCHEMBL26662175 | 0.78 | — | — | |
| SCHEMBL1687703 | 0.77 | ALOX5 (0.40) | — | |
| Hydrochloric Acid SCHEMBL9433714 | 0.77 | TAAR1 (0.48) | — | |
| SCHEMBL5199435 | 0.76 | FFAR1 (0.47) | — | |
| SCHEMBL2557799 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| US-8895585-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8809371-B2 | — | — | 2014-08-19 | — | — | US | disclosed |
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |