Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930991 | 0.89 | LMNA (0.62) | LMNATP53HBBSMN1; SMN2ENTPD1 | |
| SCHEMBL14946175 | 0.85 | ENTPD1 (0.53) | LMNATP53HBBSMN1; SMN2ENTPD1 | |
| SCHEMBL15248806 | 0.80 | LMNA (0.56) | LMNATP53HBBSMN1; SMN2ENTPD1 | |
| SCHEMBL14928421 | 0.80 | LMNA (0.56) | LMNATP53HBBSMN1; SMN2ENTPD1 | |
| SCHEMBL15071502 | 0.80 | LMNA (0.56) | LMNATP53HBBSMN1; SMN2ENTPD1 | |
| SCHEMBL14929076 | 0.77 | P2RY2 (0.44) | — | |
| SCHEMBL15456809 | 0.75 | LMNA (0.69) | LMNATP53HBBSMN1; SMN2ENTPD1 | |
| SCHEMBL15245119 | 0.75 | LMNA (0.69) | LMNATP53HBBSMN1; SMN2ENTPD1 | |
| SCHEMBL29413068 | 0.75 | LMNA (0.69) | LMNATP53HBBSMN1; SMN2ENTPD1 | |
| SCHEMBL17210941 | 0.74 | P2RY2 (0.49) | ENTPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428535-B2 | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof | MODERNA THERAPEUTICS, INC. (US) | 2016-08-30 | — | — | US | disclosed |
| US-20130115272-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | modeRNA Therapeutics (US) | 2013-05-09 | — | — | US | disclosed |