Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14924761 | 0.83 | ALDH1A1 (0.65) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL360530 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL10330147 | 0.78 | ALDH1A1 (0.69) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL14076494 | 0.73 | ALDH1A1 (0.65) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL3765154 | 0.71 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL3091939 | 0.71 | ALDH1A1 (0.65) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL3922541 | 0.68 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL2927596 | 0.68 | ALDH1A1 (0.71) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL3992021 | 0.66 | ALDH1A1 (0.83) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 | |
| SCHEMBL3915483 | 0.65 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130116267-A1 | Role of PI3K P110 Delta Signaling in Retroviral Infection and Replication | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116267-A1 | Role of PI3K P110 Delta Signaling in Retroviral Infection and Replication | PIK3R5, PIK3R4, PIK3R3 | ALDH1A1 4867/4885LMNA 3891/4885SMN1; SMN2 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.