SCHEMBL14930441

SCHEMBL14930441

COCCCCOC(=O)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
TP53 P04637 1/20 0.51
HPGD P15428 1/20 0.51
LMNA P02545 2/20 0.50
CYP1A2 P05177 2/20 0.50
TSHR P16473 2/20 0.50
CYP2C19 P33261 2/20 0.50
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
ESR1 P03372 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPK1 P28482 1/20 0.50
NR1H2 P55055 1/20 0.50
RNASEL Q05823 1/20 0.50
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
PDE4D Q08499 1/20 0.49
TDP1 Q9NUW8 3/20 0.49
STS P08842 7/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14930471 0.87 SMN1; SMN2 (0.50) SMN1; SMN2TP53HPGDTSHRHDAC3
SCHEMBL14930474 0.87 SMN1; SMN2 (0.50) SMN1; SMN2TP53HPGDTSHRHDAC3
SCHEMBL12532606 0.84 SMN1; SMN2 (0.59) SMN1; SMN2LMNACYP1A2TSHRCYP2C19
SCHEMBL14926449 0.84 MAPT (0.61) SMN1; SMN2LMNACYP1A2TSHRCYP2C19
SCHEMBL14930440 0.83 KMT2A (0.51) SMN1; SMN2HPGDLMNACYP1A2TSHR
SCHEMBL14930519 0.83 ACACB (0.48) SMN1; SMN2TP53HPGDTSHRHDAC3
SCHEMBL14926438 0.83 MAPT (0.59) SMN1; SMN2TP53LMNACYP1A2TSHR
SCHEMBL18643853 0.83 MAPT (0.59) SMN1; SMN2LMNACYP1A2TSHRCYP2C19
SCHEMBL14926434 0.83 MAPT (0.59) SMN1; SMN2TP53LMNACYP1A2TSHR
SCHEMBL14926446 0.83 MAPT (0.59) SMN1; SMN2TP53LMNACYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20160274418-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2016-09-22 US disclosed
US-9360708-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2016-06-07 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed