Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930471 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53HPGDMMP2MMP9 | |
| SCHEMBL14930519 | 0.87 | ACACB (0.48) | SMN1; SMN2TP53HPGDABCB11CYP3A4 | |
| SCHEMBL14930441 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53HPGDCYP3A4TDP1 | |
| SCHEMBL14930470 | 0.84 | NPC1 (0.61) | SMN1; SMN2ABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL14930475 | 0.84 | NPC1 (0.61) | SMN1; SMN2ABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL14930468 | 0.84 | KDM4E (0.53) | HPGDABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL14930476 | 0.84 | KDM4E (0.53) | HPGDABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL14926666 | 0.81 | ABCB11 (0.51) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL14926632 | 0.81 | ABCB11 (0.51) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL514977 | 0.81 | TP53 (0.55) | SMN1; SMN2TP53HPGDMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9939555-B2 | Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof | DIC CORPORATION (JP) | 2018-04-10 | — | — | US | disclosed |
| US-9708535-B2 | Liquid crystal alignment layer | DIC CORPORATION (JP) | 2017-07-18 | — | — | US | disclosed |
| US-9684206-B2 | Copolymer, and liquid crystal alignment layer including cured product thereof | DIC CORPORATION (JP) | 2017-06-20 | — | — | US | disclosed |
| US-20170088777-A1 | LIQUID CRYSTAL ALIGNMENT LAYER | DIC CORPORATION (JP) | 2017-03-30 | — | — | US | disclosed |
| US-20160274418-A1 | CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF | DIC CORPORATION (JP) | 2016-09-22 | — | — | US | disclosed |
| US-9360708-B2 | Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof | DIC CORPORATION (JP) | 2016-06-07 | — | — | US | disclosed |
| US-9340634-B2 | Polymer for use in liquid crystal alignment layer | DIC CORPORATION (JP) | 2016-05-17 | — | — | US | disclosed |
| US-20140221574-A1 | COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF | DIC CORPORATION (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140154428-A1 | CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF | DIC CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140121345-A1 | CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF | DIC CORPORATION (JP) | 2014-05-01 | — | — | US | disclosed |
| US-20130116396-A1 | POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER | DIC CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |