SCHEMBL14930516

SCHEMBL14930516

COCCOc1ccc2cc(OC)ccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
CYP2A6 P11509 1/20 0.54
PPARG P37231 1/20 0.53
MAPK1 P28482 3/20 0.52
KDM4E B2RXH2 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
HSD17B1 P14061 1/20 0.47
HSD17B2 P37059 1/20 0.47
RAB9A P51151 3/20 0.46
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP11B1 P15538 3/20 0.45
CYP11B2 P19099 3/20 0.45
NPC1 O15118 2/20 0.44
PTGS1 P23219 1/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
CASP3 P42574 1/20 0.44
SENP7 Q9BQF6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16305612 0.91 KDM4E (0.58) CYP1A2CYP2A6PPARGMAPK1KDM4E
SCHEMBL14231795 0.86 CA12 (0.51) MAPK1KDM4ETDP1RAB9AKMT2A
SCHEMBL14926627 0.86 CA12 (0.51) MAPK1KDM4ETDP1
SCHEMBL2214606 0.86 KDM4E (0.71) CYP1A2CYP2A6PPARGMAPK1KDM4E
SCHEMBL14926623 0.86 KDM4E (0.53) CYP1A2MAPK1KDM4ETDP1RAB9A
SCHEMBL9466144 0.84 KDM4E (0.63) CYP1A2CYP2A6PPARGMAPK1KDM4E
SCHEMBL14926620 0.84 CYP2A6 (0.50) CYP1A2CYP2A6PPARGMAPK1KDM4E
SCHEMBL10186609 0.83 MAPK1 (0.68) CYP1A2MAPK1MEN1KMT2ASMN1; SMN2
SCHEMBL25106884 0.82 KDM4E (0.47) PPARGMAPK1KDM4ETDP1RAB9A
SCHEMBL5829593 0.82 KDM4E (0.47) CYP2A6MAPK1KDM4ETDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20160274418-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2016-09-22 US disclosed
US-9360708-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2016-06-07 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed