Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13400056 | 0.87 | FOLH1 (0.49) | TSHRKMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL13400091 | 0.87 | FOLH1 (0.49) | TSHRKMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL2742777 | 0.87 | FOLH1 (0.49) | TSHRKMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL21943867 | 0.87 | KMT2A (0.49) | TSHRKMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL19594663 | 0.87 | KMT2A (0.49) | TSHRKMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL21844220 | 0.85 | KMT2A (0.50) | TSHRKMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL14864546 | 0.85 | FOLH1 (0.53) | TSHRKMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL14048625 | 0.84 | FOLH1 (0.44) | TSHRKMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL14048647 | 0.83 | FOLH1 (0.58) | TSHRFOLH1 | |
| SCHEMBL18058879 | 0.82 | TSHR (0.38) | TSHRKMT2APOLBSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8734846-B2 | Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic targeted nanoparticles | BIND BIOSCIENCES, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130115192-A1 | Methods for the Preparation of Targeting Agent Functionalized Diblock Copolymers for Use in Fabrication of Therapeutic Targeted Nanoparticles | BIND BIOSCIENCES, INC (US) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130115192-A1 | Methods for the Preparation of Targeting Agent Functionalized Diblock Copolymers for Use in Fabrication of Therapeutic Targeted Nanoparticles | GNE, PAM, EPHA2 | TSHR 1807/4885KMT2A 2240/4885POLB 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.