Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.61 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230228 | 1.00 | GRM2 (0.61) | GRM2GRM3 | |
| SCHEMBL4360136 | 0.92 | GRM2 (0.62) | GRM2GRM3 | |
| SCHEMBL232547 | 0.91 | GRM2 (0.75) | GRM2GRM3 | |
| SCHEMBL1226471 | 0.91 | GRM2 (0.75) | GRM2GRM3 | |
| SCHEMBL4967900 | 0.91 | GRM2 (0.70) | GRM2GRM3 | |
| SCHEMBL514523 | 0.91 | GRM2 (0.70) | GRM2GRM3 | |
| SCHEMBL4967909 | 0.91 | GRM2 (0.70) | GRM2GRM3 | |
| SCHEMBL5961906 | 0.88 | GRM2 (0.80) | GRM2GRM3 | |
| SCHEMBL7070920 | 0.88 | GRM2 (0.80) | GRM2GRM3 | |
| SCHEMBL231526 | 0.88 | GRM2 (0.80) | GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2287147-B1 | 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2013-05-15 | — | — | EP | disclosed |