Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656950 | 1.00 | PTGS1 (0.35) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL29349420 | 0.94 | PTGS1 (0.39) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL7790458 | 0.94 | PTGS1 (0.39) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL27677168 | 0.83 | PTGS1 (0.34) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL27677171 | 0.83 | PTGS1 (0.34) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL6430308 | 0.82 | PTGS1 (0.34) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL1493232 | 0.80 | PTGS1 (0.45) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL4082389 | 0.75 | OR51E2 (0.33) | — | |
| SCHEMBL15756799 | 0.75 | OR51E2 (0.33) | — | |
| SCHEMBL9802393 | 0.74 | PTGS1 (0.34) | PTGS1SLC7A11ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154517-A1 | IMMUNOCYTOKINE COMBINATION THERAPY | PHILOGEN SPA (IT) | 2018-08-30 | — | — | WO | disclosed |
| US-8491906-B2 | Selective targeting of tumor vasculature using antibody molecules | PHILOGEN S.P.A. (IT) | 2013-07-23 | — | — | US | disclosed |
| EP-1663320-B1 | TARGETING OF TUMOR VASCULATURE USING RADIOLABELLED ANTIBODY L19 AGAINST FIBRONECTIN ED-B | PHILOGEN SPA (IT) | 2011-03-02 | — | — | EP | disclosed |
| EP-2246070-A2 | Targeting of tumor vasculature using radiolabelled antibody l19 against fibronectin ed-b | Philogen S.p.A. (IT) | 2010-11-03 | — | — | EP | disclosed |
| EP-2174958-A1 | Antibodies derived from anti ed-b l19 and targeting tumor vasculature | Philogen S.p.A. (IT) | 2010-04-14 | — | — | EP | disclosed |
| EP-1483297-B1 | ANTIBODIES DERIVED FROM ANTI ED-B L19 AND TARGETING TUMOR VASCULATURE | PHILOGEN SPA (IT) | 2009-12-23 | — | — | EP | disclosed |
| CN-100535013-C | Selective targeting of tumor vasculature using antibody molecules | PHILOGEN S R L SCHERING AG (IT) | 2009-09-02 | — | — | CN | disclosed |
| US-20090214423-A1 | SELECTIVE TARGETING OF TUMOR VASCULATURE USING RADIOLABELLED ANTIBODY MOLECULES | BORSI LAURA | 2009-08-27 | — | — | US | disclosed |
| CN-100482285-C | Targeting of tumor vasculature using radiolabelled antibody l19 against fibronectin ED-B | PHILOGEN S P A SCHERING AG (IT) | 2009-04-29 | — | — | CN | disclosed |
| CN-1849144-A | Targeting of tumor vasculature using radiolabelled antibody l19 against fibronectin ED-B | PHILOGEN SPA (IT) | 2006-10-18 | — | — | CN | disclosed |
| EP-1663320-A1 | TARGETING OF TUMOR VASCULATURE USING RADIOLABELLED ANTIBODY L19 AGAINST FIBRONECTIN ED-B | Philogen S.p.A. (IT) | 2006-06-07 | — | — | EP | disclosed |
| US-20060057146-A1 | Selective targeting of tumor vasculature using antibody molecules | PHILOGEN (IT) | 2006-03-16 | — | — | US | disclosed |
| WO-2003076469-A9 | ANTIBODIES DERIVED ROM ANTI ED-B L19 AND TARGETING TUMOR VASCULATURE | PHILOGEN SPA (IT) | 2005-09-29 | — | — | WO | disclosed |
| CN-1639195-A | Selective targeting of tumor vasculature using antibody molecules | PHILOGEN SRL (IT) | 2005-07-13 | — | — | CN | disclosed |
| US-20050074401-A1 | Selective targeting of tumor vasculature using radiolabelled antibody molecules | SCHERING AG (DE) | 2005-04-07 | — | — | US | disclosed |
| WO-2005023318-A1 | TARGETING OF TUMOR VASCULATURE USING RADIOLABELLED ANTIBODY L19 AGAINST FIBRONECTIN ED-B | PHILOGEN S.P.A (IT) | 2005-03-17 | — | — | WO | disclosed |
| EP-1514561-A1 | Targeting of tumor vasculature using radiolabelled antibody L19 against fibronectin ED-B | Philogen S.p.A. (IT) | 2005-03-16 | — | — | EP | disclosed |
| EP-1483297-A2 | ANTIBODIES DERIVED FROM ANTI ED-B L19 AND TARGETING TUMOR VASCULATURE | Philogen S.p.A. (IT) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003076469-A2 | ANTIBODIES DERIVED ROM ANTI ED-B L19 AND TARGETING TUMOR VASCULATURE | PHILOGEN S.P.A. (IT) | 2003-09-18 | — | — | WO | disclosed |